Determination of surface-induced platelet activation by applying time-dependency dissipation factor versus frequency using quartz crystal microbalance with dissipation
نویسندگان
چکیده
منابع مشابه
Determination of surface-induced platelet activation by applying time-dependency dissipation factor versus frequency using quartz crystal microbalance with dissipation.
Platelet adhesion and activation rates are frequently used to assess the thrombogenicity of biomaterials, which is a crucial step for the development of blood-contacting devices. Until now, electron and confocal microscopes have been used to investigate platelet activation but they failed to characterize this activation quantitatively and in real time. In order to overcome these limitations, qu...
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Interactions between blood platelets and nanoparticles have both pharmacological and toxicological significance and may lead to platelet activation and aggregation. Platelet aggregation is usually studied using light aggregometer that neither mimics the conditions found in human microvasculature nor detects microaggregates. A new method for the measurement of platelet microaggregation under flo...
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The dissipation factor and subsequently the characterization of the viscoelasticity of deposition films have become crucial for the study of biomolecular adsorption. Most of the commercial quartz crystal microbalance (QCM) systems offer this feature, but it has not been incorporated in open source systems. This article describes the design, construction, and simulation of an open source QCM mod...
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ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2011
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2010.0617